Identification and Functional Characterization of a Novel Mitochondrial Carrier for Citrate and Oxoglutarate in S. Cerevisiae*

IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF A NOVEL MITOCHONDRIAL CARRIER FOR CITRATE AND OXOGLUTARATE IN S. CEREVISIAE* Alessandra Castegna#, Pasquale Scarcia#, Gennaro Agrimi, Luigi Palmieri, Hanspeter Rottensteiner, Iolanda Spera, Lucrezia Germinario, Ferdinando Palmieri From the Department of Pharmaco-Biology, Laboratory of Biochemistry and Molecular Biology, University of Bari, 70125 Bari, Italy, Institut für Physiologische Chemie, Abteilung Systembiochemie, RuhrUniversität Bochum, 44780 Bochum, Germany, and the CNR Institute of Biomembranes and Bioenergetics, 70125 Bari, Italy Running head: Mitochondrial citrate-oxoglutarate carrier in S. cerevisiae These authors contributed equally to this work. Address correspondence to: Prof. Ferdinando Palmieri, Via Orabona 4, 70125 Bari, Italy, Tel. +39(0)805443374; Fax +39(0)805442770; E-mail: [email protected]